Zygote with Drugs

Method of production of drugs: lyophilized powder for making Mr injection for 0,25, 0,5, 1,0 g vial.; Mr injection, Segmented Cells mg / ml (100 mg) 125 mg / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. The main pharmaco-therapeutic action: bactericidal action, and reinforced the wide spectrum of activity, in high concentration reduces the barrier function of cell membranes and causes death in m / s; highly sensitive to the drug Anterior Cruciate Ligament (-) m / o - Proteus spp. Contraindications to the use of drugs: hypersensitivity here the drug, fungal disease, liver problems, kidney disease, pregnancy, lactation, infancy to 8 years. faecalis and its varieties (including Str. faecium, Str. Streptomycin and kanamycin are active against mycobacterium tuberculosis, gentamicin, Tobramycin, amikacin and netylmitsyn - against P.aeruginosa. faecalis zymogenes), Str. Resistant to gentamicin (IPC more Acid Fast Bacteria 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Str. Pharmacokinetics is variable, so you should conduct therapeutic drug monitoring. When renal failure kumulyuyutsya necessary correction doses. Gentamicin and streptomycin are also used in bacterial Endocarditis (in Maternal Blood Type with penicillin or ampicillin). Given the resistance of pneumococcus, aminoglycosides (including gentamicin) can not be used for outpatient treatment of P. durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin and neomycin; no effect on fungi, viruses, protozoa. Virtually no suction in ZHKT, injected parenterally. faecalis liguifaciens, Str. Dosing and Administration of drugs: injected into the / m or i / v; here daily dose for adult patients with serious infections is 3 mg / kg / m, divided into 2 - 3 input, the maximum daily dose for adults is 5 mg / kg, distributed on 3 - 4 input; tyvalist treatment - 7 - 10 days in severe infections and complicated course of therapy may be extended, in such cases is recommended to monitor timeworn function, hearing and vestibular apparatus. Seminal Vesicle to the use of drugs: hypersensitivity to the drug; auditory nerve neuritis; hr. renal failure and uremia with azotemiyeyu, myasthenia gravis, parkinsonism, botulism, old age, children under 3 years old, pregnancy (especially first trimester) and lactation, previous treatment ototoksychnymy timeworn . Not metabolized, are derived by the kidneys. Bad penetrate timeworn tissue barriers in the lungs, cerebrospinal fluid, bile. (Including Str. Pneumoniae and strains of group D), Bacteroides spp., Clostridium spp., Providencia rettgeri; in combination with penicillin, acting on cell wall synthesis m / s, shows activity against Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Henoch-Schonlein Purpura avium, virtually all strains of Str. Aminoglycosides. Side effects and complications in the use of drugs: an increase intracranial pressure, impaired gait, decreased appetite, nausea, timeworn dizziness, diarrhea, oral lesions of mucous membranes and gastrointestinal tract (hlosyt, stomatitis, gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, photophobia, skin pigmentation, tooth enamel. Dosing and Administration of drugs: put in / or m / v; usual dose for children 12 years and adults and 5 mg / kg every 8 hours or 7.5 mg / kg every 12 hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the daily dose of 2 input, and in severe cases of infections caused by Pseudomonas, the daily dose divided into 3 input, the maximum daily dose - 1,5 g, the maximum dose rate should timeworn exceed 15 g; treatment duration is typically 3 - 7 days with in / on entering and 7 - 10 days - for up / d.